drug_type
RELEVANT_DRUG
intervention_type
cellular therapy (autologous T-cell therapy)
drug_description
Autologous, expanded tumor-draining lymph node–derived T cells administered as adoptive cell therapy.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
CULTURED CELLS
drug_class
Unedited cells
drug_delivery_route
Intravenous
drug_mechanism_of_action
Autologous T cells harvested from tumor-draining lymph nodes are expanded ex vivo and reinfused. These lymphocytes are enriched for tumor-primed, antigen-specific T cells that recognize tumor antigens via their native TCRs, then mediate cytotoxic killing and cytokine-driven immune responses against tumor cells.
drug_name
Tumor-draining lymph node–derived lymphocytes (LNLs)
nct_id_drug_ref
NCT05981001