drug_type
RELEVANT_DRUG
intervention_type
biologic (antibody-drug conjugate)
drug_description
TROP2-directed antibody-drug conjugate; a humanized anti-TROP2 monoclonal antibody that is internalized upon binding and releases a topoisomerase I inhibitor payload to induce DNA damage and cell death.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Humanized anti-TROP2 monoclonal antibody binds TROP2 on tumor cells, is internalized, and releases a topoisomerase I inhibitor payload that induces DNA damage and tumor cell death.
drug_name
Sacituzumab tirumotecan (MK-2870/SKB264)
nct_id_drug_ref
NCT06074588