drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Antibody-drug conjugates targeting CD79b (a B-cell receptor component) that internalize and release cytotoxins to kill B-cell lymphomas.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Monoclonal antibody binds CD79b on B-cell receptor, is internalized, and releases its linked cytotoxic payload intracellularly to kill malignant B cells (e.g., via microtubule/DNA damage and apoptosis), with potential Fc-mediated effector contributions.
drug_name
CD79b-directed antibody-drug conjugates (ADC)
nct_id_drug_ref
NCT06008691