drug_type
RELEVANT_DRUG
intervention_type
Monoclonal antibody
drug_description
Anti-CD47 monoclonal antibody immunotherapy that blocks the CD47–SIRPα 'don't-eat-me' signal, enhancing macrophage-mediated phagocytosis of leukemia cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Anti-CD47 monoclonal antibody that blocks the CD47-SIRPa interaction, removing the 'don't eat me' signal and promoting macrophage-mediated phagocytosis of leukemia cells.
drug_name
AK117
nct_id_drug_ref
NCT06387420