drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
Biologic antibodies intended to bind glioblastoma-specific cell-surface antigens to block oncogenic/survival receptor signaling and recruit immune effector functions such as ADCC and CDC.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Not specified
drug_mechanism_of_action
Unconjugated monoclonal antibodies that bind glioblastoma-restricted cell-surface antigens to block oncogenic/survival receptor signaling and trigger Fc-mediated immune effector functions (ADCC and CDC) to eliminate tumor cells.
drug_name
Therapeutic monoclonal antibodies
nct_id_drug_ref
NCT05917821