drug_type
RELEVANT_DRUG
intervention_type
monoclonal antibody (anti-MUC1)
drug_description
Humanized IgG1 monoclonal antibody targeting MUC1 on cancer cells; engages Fcγ receptor–bearing effector cells (e.g., NK cells/macrophages) to mediate ADCC/CDC.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
CYTOTOXIC ANTIBODY
drug_class
Cytotoxic protein
drug_delivery_route
Intravenous
drug_mechanism_of_action
Humanized IgG1 monoclonal antibody targeting MUC1 on tumor cells; engages Fcγ receptor–bearing effector cells (e.g., NK cells, macrophages) to induce antibody‑dependent cellular cytotoxicity and complement‑dependent cytotoxicity, resulting in tumor cell killing.
drug_name
BGB-B3227
nct_id_drug_ref
NCT06540066