drug_type
RELEVANT_DRUG
intervention_type
TCR-based bispecific T-cell engager biologic
drug_description
A TCR-based bispecific T-cell engager that binds the MAGE-A4 peptide presented by HLA-A*02 on tumor cells and CD3 on T cells to redirect and activate cytotoxic T cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Intravenous
drug_mechanism_of_action
TCR-based bispecific that binds the MAGE-A4 peptide presented by HLA-A*02 on tumor cells and CD3 on T cells, redirecting and activating polyclonal cytotoxic T cells to induce tumor cell lysis.
drug_name
RO7617991
nct_id_drug_ref
NCT06372574