drug_type
RELEVANT_DRUG
intervention_type
polyclonal antibody (biologic)
drug_description
Polyclonal antilymphocyte/antithymocyte globulin that depletes T cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antilymphocyte Serum
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Polyclonal anti–T-lymphocyte immunoglobulin that binds multiple T‑cell surface antigens and induces complement-dependent cytotoxicity and Fc-mediated clearance (ADCC/phagocytosis), leading to rapid T‑cell depletion and immunosuppression.
drug_name
ATG (antithymocyte globulin)
nct_id_drug_ref
NCT05669001