drug_type
RELEVANT_DRUG
intervention_type
Biologic drug
drug_description
A bispecific T-cell engager antibody targeting BCMA and CD3 that redirects T cells to kill BCMA-positive myeloma cells via immune synapse formation and cytokine-mediated cytotoxicity.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Bispecific
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Intravenous
drug_mechanism_of_action
Bispecific antibody that simultaneously binds BCMA on myeloma cells and CD3 on T cells, forming an immune synapse that redirects T-cell cytotoxicity and cytokine release to kill BCMA-positive plasma cells.
drug_name
Alnuctamab (BMS-986349/CC-93269)
nct_id_drug_ref
NCT06163898