drug_type
RELEVANT_DRUG
intervention_type
monoclonal antibody
drug_description
Cetuximab-like anti-EGFR monoclonal antibody that binds EGFR to inhibit ligand-driven signaling and mediates Fc-dependent cytotoxicity (ADCC, ADCP).
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
anti-EGFR
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Unconjugated monoclonal antibody that binds EGFR, blocks ligand-driven receptor activation and downstream signaling (e.g., RAS/MAPK, PI3K/AKT), and engages Fc receptors to elicit immune effector functions including ADCC and ADCP against EGFR-expressing tumor cells.
drug_name
anti-EGFR
nct_id_drug_ref
NCT06508606