drug_type
RELEVANT_DRUG
intervention_type
biologic
drug_description
Polyclonal antibody preparation that depletes T cells to reduce graft rejection and GVHD.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antithymocyte Globulin
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Polyclonal anti–T-cell immunoglobulins that bind multiple T-cell surface antigens and deplete T cells via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and phagocytic clearance, producing immunosuppression to prevent graft rejection and GVHD.
drug_name
Anti-thymocyte globulin (ATG)
nct_id_drug_ref
NCT06674382