drug_type
RELEVANT_DRUG
intervention_type
Cellular therapy (autologous CAR T cells)
drug_description
Autologous, genetically engineered T cells expressing a chimeric antigen receptor targeting MUC16 to recognize and kill MUC16-positive tumor cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
CAR T
drug_class
Cellular Therapy
drug_delivery_route
Intravenous
drug_mechanism_of_action
Autologous T cells engineered to express a chimeric antigen receptor that binds MUC16 on tumor cells; CAR signaling activates the T cells to proliferate, release cytotoxic mediators, and lyse MUC16-positive cancer cells.
drug_name
27T51 anti-MUC16 CAR T cells
nct_id_drug_ref
NCT06469281