drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Also known as PRO1107, a PTK7-targeted monoclonal antibody–drug conjugate (ADC) that binds PTK7 on tumor cells, is internalized, and releases a cytotoxic payload to induce tumor cell death.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
PTK7-targeted monoclonal antibody-drug conjugate that binds PTK7 on tumor cells, is internalized, and releases an intracellular cytotoxic payload via linker cleavage, leading to tumor cell death.
drug_name
GEN1107
nct_id_drug_ref
NCT06171789