drug_type
RELEVANT_DRUG
intervention_type
Biologic (monoclonal antibody), intravenous infusion
drug_description
An intravenous monoclonal antibody that binds TRBV9 on the T-cell receptor beta chain to selectively target TRBV9-expressing T lymphocytes, aiming to modulate or deplete these cells and reduce TCR-driven pathogenic responses in axial spondyloarthritis.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Monoclonal antibody that binds the TRBV9 region of the T-cell receptor beta chain to selectively target TRBV9-expressing T lymphocytes, leading to modulation or depletion of these cells and reduction of pathogenic TCR-driven responses in axial spondyloarthritis.
drug_name
BCD-180
nct_id_drug_ref
NCT06333210