drug_type
RELEVANT_DRUG
intervention_type
monoclonal antibody (anti-GD2)
drug_description
Humanized IgG1 anti-GD2 monoclonal antibody that binds GD2 on neuroblastoma cells and mediates Fc receptor–dependent ADCC and complement-dependent cytotoxicity.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
naxitamab
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Humanized IgG1 anti-GD2 monoclonal antibody that binds GD2 on neuroblastoma cells and induces immune-mediated killing via Fcγ receptor–dependent antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC).
drug_name
Naxitamab (hu3F8)
nct_id_drug_ref
NCT06013618