drug_type
RELEVANT_DRUG
intervention_type
Biologic (personalized mRNA vaccine)
drug_description
Personalized mRNA neoantigen cancer vaccine that delivers patient-specific tumor neoantigens to dendritic cells to enhance MHC I/II presentation and prime/expand tumor-specific CD8+ and CD4+ T cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Cancer Vaccines
drug_category
mRNA VACCINE
drug_class
Vaccine
drug_delivery_route
Unknown
drug_mechanism_of_action
Personalized mRNA encoding patient-specific tumor neoantigens is delivered to dendritic cells, translated into neoantigen peptides, and presented on MHC I and II to prime and expand tumor-specific CD8+ and CD4+ T cells, generating antitumor immunity.
drug_name
XH001
nct_id_drug_ref
NCT06353646