drug_type
RELEVANT_DRUG
intervention_type
biosimilar monoclonal antibody
drug_description
Biosimilar to rituximab; anti-CD20 monoclonal antibody that depletes B cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Rituximab
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Biosimilar to rituximab; a chimeric anti‑CD20 monoclonal antibody that binds CD20 on pre‑B and mature B cells and depletes them primarily via antibody‑dependent cellular cytotoxicity and complement‑dependent cytotoxicity, with additional direct apoptotic signaling, thereby reducing B‑cell–mediated immune responses.
drug_name
Rituximab biosimilar
nct_id_drug_ref
NCT06078696