drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Anti-CD20 monoclonal antibody intended to deplete CD20-positive B cells and lessen autoimmune-mediated platelet destruction.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Anti-CD20 monoclonal antibody that binds CD20 on pre-B and mature B cells and depletes them via antibody-dependent cellular cytotoxicity, complement-dependent cytotoxicity, and apoptosis, reducing autoantibody production and immune-mediated platelet destruction.
drug_name
Ortuzumab
nct_id_drug_ref
NCT05718856