drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
A TROP2-targeted antibody-drug conjugate comprising an anti-TROP2 monoclonal antibody linked to a cytotoxic payload that is delivered to TROP2-expressing tumor cells upon internalization.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Anti-TROP2 monoclonal antibody linked to a cytotoxic payload; binds TROP2 on tumor cells, is internalized, and releases the payload intracellularly to induce tumor cell death (e.g., via DNA damage or microtubule disruption), with potential Fc-mediated effector contributions.
drug_name
TROP2 ADC
nct_id_drug_ref
NCT05824325