drug_type
RELEVANT_DRUG
intervention_type
radioimmunotherapy (radiolabeled monoclonal antibody)
drug_description
Radiolabeled anti-PSMA monoclonal antibody that binds PSMA on prostate cancer cells and delivers lutetium-177 beta radiation to induce DNA damage and tumor cell death.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal, Radiolabeled
drug_category
RADIOIMMUNOCONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
A radiolabeled anti-PSMA monoclonal antibody that binds PSMA on prostate cancer cells and delivers lutetium-177 beta radiation, causing localized DNA damage (including double-strand breaks) and tumor cell death.
drug_name
177Lu-DOTA-rosopatamab (TLX591)
nct_id_drug_ref
NCT04876651