drug_type
RELEVANT_DRUG
intervention_type
Antibody-drug conjugate
drug_description
Monoclonal antibodies linked to cytotoxic payloads that deliver intracellular chemotherapy to antigen-expressing lymphoma cells.
nci_thesaurus_concept_id
C129823
nci_thesaurus_definition
Any tumor-targeting antibody conjugated to a cytotoxic agent that exerts an antineoplastic effect.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Tumor-targeting monoclonal antibodies linked to a cytotoxic payload bind an antigen on lymphoma cells, internalize, and release the payload intracellularly to damage DNA or microtubules and induce apoptosis, enabling antigen-directed chemotherapy with potential bystander effects.
drug_name
Antibody-drug conjugates
nct_id_drug_ref
NCT06202885