drug_type
RELEVANT_DRUG
intervention_type
Polyclonal antibody (biologic)
drug_description
Rabbit polyclonal anti-T-cell globulin used for in vivo T-cell depletion and immunosuppression.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Thymoglobulin
drug_category
CYTOTOXIC ANTIBODY
drug_class
Cytotoxic protein
drug_delivery_route
Intravenous
drug_mechanism_of_action
Rabbit polyclonal anti‑thymocyte globulin that binds multiple T‑cell surface antigens (e.g., CD2, CD3, CD4, CD8, adhesion/HLA molecules) and depletes T lymphocytes via complement‑dependent cytotoxicity, antibody‑dependent cellular cytotoxicity, and apoptosis, resulting in potent in vivo T‑cell immunosuppression.
drug_name
Thymoglobulin (rabbit anti-thymocyte globulin)
nct_id_drug_ref
NCT05735717