drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Fc-enhanced anti-CTLA-4 monoclonal antibody that promotes T-cell priming and depletes intratumoral Tregs via ADCC, boosting CD8+ T-cell responses.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Fc-enhanced anti-CTLA-4 monoclonal antibody that blocks CTLA-4 to promote T-cell priming/activation and leverages Fc-mediated ADCC to deplete intratumoral Tregs, boosting CD8+ T-cell responses.
drug_name
Botensilimab (AGEN1181)
nct_id_drug_ref
NCT06300463