drug_type
RELEVANT_DRUG
intervention_type
biologic antibody - immunosuppressant
drug_description
Polyclonal antibody preparation that depletes T cells for GVHD prophylaxis.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antithymocyte Globulin
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Polyclonal IgG directed against multiple T-cell antigens that binds and depletes T cells via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and induction of apoptosis, leading to immunosuppression and GVHD prophylaxis.
drug_name
Antithymocyte globulin
nct_id_drug_ref
NCT06571825