drug_type
RELEVANT_DRUG
intervention_type
Biologic (monoclonal antibody)
drug_description
Humanized, Fc-engineered anti-CTLA-4 monoclonal antibody that enhances T-cell priming by blocking CTLA-4 and may deplete CTLA-4high regulatory T cells via Fc-mediated effector functions.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal, Humanized
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Humanized, Fc‑engineered anti‑CTLA‑4 monoclonal antibody that blocks CTLA‑4 to enhance T‑cell priming/activation and leverages Fc‑mediated effector functions (e.g., ADCC/ADCP) to deplete CTLA‑4high regulatory T cells, thereby augmenting antitumor immunity.
drug_name
IMM27M
nct_id_drug_ref
NCT06764836