drug_type
RELEVANT_DRUG
intervention_type
Biologic; bispecific T-cell–engaging monoclonal antibody
drug_description
An IV BCMA×CD3 bispecific T‑cell–engaging monoclonal antibody that redirects CD3+ T cells to kill BCMA-expressing plasma cells, aiming to deplete IgE-producing plasma cells and lower food-specific IgE.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Intravenous
drug_mechanism_of_action
BCMA×CD3 bispecific T‑cell–engaging monoclonal antibody that binds BCMA on plasma cells and CD3 on T cells, bringing them into proximity to activate cytotoxic T cells and kill BCMA‑expressing antibody‑secreting plasma cells, thereby depleting IgE‑producing plasma cells and lowering food‑specific IgE.
drug_name
linvoseltamab
nct_id_drug_ref
NCT06369467