drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Also known as AMT-754, ADCE-T02 is an intravenously administered antibody-drug conjugate (ADC) targeting Tissue Factor (TF; CD142/F3) on tumor cells. After binding and internalization, it releases a cytotoxic payload to induce cancer cell death.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Monoclonal antibody targets Tissue Factor (TF/CD142) on tumor cells; after binding and internalization, the ADC releases an intracellular cytotoxic payload that kills the cancer cell.
drug_name
ADCE-T02
nct_id_drug_ref
NCT06597721