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drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Investigational intravenous antibody-drug conjugate targeting a tumor-associated surface antigen; upon binding and internalization, it releases a cytotoxic payload to kill antigen-expressing tumor cells. Being evaluated in a first-in-human Phase 1 dose escalation/expansion study in advanced solid tumors.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
An intravenous antibody–drug conjugate whose monoclonal antibody binds a tumor-associated surface antigen, is internalized, and releases a linked cytotoxic payload inside the cell to kill antigen-expressing tumor cells.
drug_name
FZ-AD004
nct_id_drug_ref
NCT05914545