drug_type
RELEVANT_DRUG
intervention_type
Antibody-drug conjugate (ADC)
drug_description
An intravenously administered biparatopic anti-5T4 (TPBG) antibody-drug conjugate that binds two epitopes on 5T4 to enhance binding/internalization and delivers an intracellular cytotoxic payload to kill 5T4-expressing tumor cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
JK06 is a biparatopic anti‑5T4 (TPBG) antibody–drug conjugate that binds two distinct epitopes on 5T4 to enhance binding and internalization, then releases an intracellular cytotoxic payload to kill 5T4‑expressing tumor cells.
drug_name
JK06
nct_id_drug_ref
NCT06667960