drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Investigational CD30-directed antibody-drug conjugate (SGN-35T) administered intravenously as monotherapy; a monoclonal antibody binds CD30 on tumor cells, is internalized, and releases a cytotoxic payload to induce tumor cell death in relapsed/refractory CD30-positive lymphomas.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
CD30-targeted monoclonal antibody–drug conjugate that binds CD30 on tumor cells, is internalized, and releases a cytotoxic payload intracellularly to induce death of CD30-positive malignant cells.
drug_name
PF-08046045
nct_id_drug_ref
NCT06120504