drug_type
RELEVANT_DRUG
intervention_type
Polyclonal antibody biologic
drug_description
Polyclonal rabbit antithymocyte globulin; IV antibody biologic that depletes T cells via complement-mediated lysis, opsonization, and apoptosis, and can modulate/deplete other leukocyte subsets.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
thymoglobulin
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Polyclonal rabbit antithymocyte immunoglobulin that binds multiple T‑cell surface antigens, causing complement-mediated lysis, opsonization/ADCC, and apoptosis to deplete T lymphocytes; can also modulate or deplete other leukocyte subsets, resulting in immunosuppression.
drug_name
RATG (Thymoglobulin)
nct_id_drug_ref
NCT06374095