drug_type
RELEVANT_DRUG
intervention_type
Antibody–drug conjugate (anti-TROP2)
drug_description
Antibody–drug conjugate targeting TROP2; internalizes and releases a topoisomerase I inhibitor payload to induce DNA damage and apoptosis (possible bystander effect).
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Anti-TROP2 antibody–drug conjugate that binds TROP2 on tumor cells, is internalized, and releases a topoisomerase I inhibitor payload to induce DNA damage and apoptosis, with potential bystander effect.
drug_name
Sacituzumab Tirumotecan (sac-TMT)
nct_id_drug_ref
NCT06469944