drug_type
RELEVANT_DRUG
intervention_type
cellular immunotherapy (adoptive T-cell therapy)
drug_description
Autologous T-cell product expanded ex vivo; provides tumor-reactive lymphocytes that mediate TCR-dependent cytotoxicity as adoptive cell therapy.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
T-Lymphocytes
drug_category
TCR SELECTED T CELLS
drug_class
Unedited cells
drug_delivery_route
Intravenous
drug_mechanism_of_action
Autologous tumor-draining lymph node–derived T cells expanded ex vivo and reinfused to provide tumor-reactive lymphocytes that recognize tumor antigens via native TCRs and kill target cells through perforin/granzyme cytotoxicity and cytokine-mediated immune activation.
drug_name
Tumor-draining lymph node-derived lymphocyte (LNL)
nct_id_drug_ref
NCT06121570