drug_type
RELEVANT_DRUG
intervention_type
adenoviral cancer vaccine
drug_description
Adenoviral (Ad5) therapeutic cancer vaccine encoding CEA, MUC1, and brachyury to prime and expand antigen-specific CD4+/CD8+ T cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Brachyury Protein
drug_category
GENE THERAPY
drug_class
Vaccine
drug_delivery_route
Subcutaneous
drug_mechanism_of_action
Non-replicating adenoviral (Ad5) therapeutic cancer vaccine encoding CEA, MUC1, and brachyury. Transduces antigen-presenting cells to express these tumor antigens, leading to MHC I/II presentation and priming/expansion of antigen-specific CD8+ and CD4+ T cells that recognize and kill antigen-expressing tumor cells.
drug_name
TriAdeno vaccine (CEA/MUC1/Brachyury)
nct_id_drug_ref
NCT06149481