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drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
An intravenous HER2-targeted monoclonal antibody–drug conjugate (ADC) dosed 5.4 mg/kg every 3 weeks; binds HER2 (ERBB2) on tumor cells, is internalized, and releases a DNA-damaging cytotoxic payload that inhibits proliferation, leading to tumor cell death; designed for HER2-expressing and HER2-low solid tumors.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
HER2-targeted monoclonal antibody–drug conjugate that binds HER2 (ERBB2) on tumor cells, is internalized, and releases a DNA-damaging cytotoxic payload, inhibiting proliferation and inducing tumor cell death in HER2-expressing and HER2-low solid tumors.
drug_name
FDA022-BB05
nct_id_drug_ref
NCT06413615