drug_type
RELEVANT_DRUG
intervention_type
Cellular therapy (CAR-M)
drug_description
PBMC-derived chimeric antigen receptor macrophage (CAR-M) cell therapy targeting mesothelin; designed to recognize mesothelin-positive tumor cells, enhance phagocytosis, secrete inflammatory cytokines, and present tumor antigens to T cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
CAR M
drug_class
Cellular Therapy
drug_delivery_route
Intravenous
drug_mechanism_of_action
PBMC-derived macrophages engineered to express an anti-mesothelin chimeric antigen receptor that recognizes mesothelin-positive tumor cells, enhances phagocytosis, secretes pro-inflammatory cytokines, and presents tumor antigens to activate T cells and remodel the tumor microenvironment.
drug_name
SY001
nct_id_drug_ref
NCT06562647