drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
Humanized anti-HER2 monoclonal antibody that inhibits HER2 signaling/dimerization and mediates ADCC.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Trastuzumab
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Subcutaneous
drug_mechanism_of_action
Humanized anti-HER2 (ERBB2) IgG1 monoclonal antibody that binds the HER2 extracellular domain, blocks receptor activation and dimerization, downregulates HER2 signaling, and engages Fcγ-mediated antibody-dependent cellular cytotoxicity (ADCC), leading to tumor cell death.
drug_name
Trastuzumab (subcutaneous)
nct_id_drug_ref
NCT06483386