drug_type
RELEVANT_DRUG
intervention_type
Monoclonal antibody
drug_description
Anti-CD47 monoclonal antibody that blocks the CD47–SIRPα 'don't-eat-me' signal to enhance macrophage phagocytosis and antigen presentation.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Anti-CD47 monoclonal antibody that blocks the CD47–SIRPα interaction, removing the tumor cell 'don't-eat-me' signal to promote macrophage phagocytosis and enhance antigen presentation, supporting innate and adaptive antitumor immunity.
drug_name
ligufalimab (AK117)
nct_id_drug_ref
NCT06601335