drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
A fully humanized IgG1 antibody–drug conjugate targeting B7-H3 (CD276). Upon binding to B7-H3 on tumor cells, it is internalized and releases a cytotoxic payload, leading to selective killing of B7‑H3–expressing cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Fully humanized IgG1 ADC targeting B7-H3 (CD276); upon binding to B7-H3 on tumor cells, the complex is internalized and releases a cytotoxic payload, selectively killing B7-H3–expressing tumor cells.
drug_name
ILB-3101
nct_id_drug_ref
NCT06426680