drug_type
RELEVANT_DRUG
intervention_type
Monoclonal antibody (bNAb)
drug_description
Intravenous broadly neutralizing monoclonal antibody targeting conserved HIV-1 Env epitopes; blocks viral entry and enables Fc-mediated clearance of infected cells.
nci_thesaurus_concept_id
C188593
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Broadly neutralizing monoclonal antibody that binds conserved epitopes on the HIV-1 envelope (Env) glycoprotein, neutralizing virus by blocking attachment/fusion and entry into CD4+ T cells; Fc region can mediate effector functions (e.g., ADCC/ADCP/complement) to promote clearance of infected cells and virions.
drug_name
Zinlirvimab
nct_id_drug_ref
NCT05729568