drug_type
RELEVANT_DRUG
intervention_type
Monoclonal antibody
drug_description
A chimeric anti-CD20 IgG1 monoclonal antibody that depletes CD20-positive B cells via antibody-dependent cellular cytotoxicity, complement-dependent cytotoxicity, and apoptosis.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Rituximab
drug_category
CYTOTOXIC ANTIBODY
drug_class
Cytotoxic protein
drug_delivery_route
Intravenous
drug_mechanism_of_action
Rituximab is a chimeric anti-CD20 IgG1 monoclonal antibody that binds CD20 on B lymphocytes and depletes CD20-positive cells through antibody-dependent cellular cytotoxicity, complement-dependent cytotoxicity, and induction of apoptosis.
drug_name
Rituximab (Rituxan)
nct_id_drug_ref
NCT06263491