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drug_type
RELEVANT_DRUG
intervention_type
Bispecific antibody
drug_description
Bispecific antibodies that bind BCMA on myeloma cells and CD3 on T cells to redirect cytotoxic T cells to tumor.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Bispecific
drug_category
BISPECIFIC T ENGAGER
drug_class
Engager
drug_delivery_route
Not Specified
drug_mechanism_of_action
Bispecific antibody that simultaneously binds BCMA on myeloma cells and CD3 on T cells, physically bringing T cells into contact with tumor cells to trigger TCR signaling, immune synapse formation, T‑cell activation and degranulation, resulting in MHC‑independent lysis of BCMA‑expressing myeloma cells.
drug_name
BCMA×CD3 bispecific T-cell engagers
nct_id_drug_ref
NCT06205823