drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
A PTK7-targeted antibody–drug conjugate administered intravenously; the monoclonal antibody binds PTK7 on tumor cells, is internalized, and releases a cytotoxic payload to induce tumor cell death in PTK7-expressing solid tumors.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
PTK7-targeted monoclonal antibody linked to a cytotoxic payload; after binding PTK7 on tumor cells, the ADC is internalized and releases its payload intracellularly, causing cytotoxicity and death of PTK7-expressing tumor cells.
drug_name
DAY301
nct_id_drug_ref
NCT06752681