drug_type
RELEVANT_DRUG
intervention_type
polyclonal antibody (biologic)
drug_description
Rabbit polyclonal anti-thymocyte globulin that depletes T cells to prevent rejection and GVHD.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antithymocyte Globulin
drug_category
CYTOTOXIC ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Rabbit polyclonal anti-thymocyte IgG that binds multiple T-cell surface antigens and depletes T cells via complement-dependent cytotoxicity, antibody-dependent cellular cytotoxicity, and apoptosis, producing immunosuppression to prevent rejection and GVHD.
drug_name
Thymoglobulin (ATG)
nct_id_drug_ref
NCT06872333