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drug_type
RELEVANT_DRUG
intervention_type
Drug
drug_description
An investigational anti-HER2 (ERBB2) antibody–drug conjugate administered intravenously every 21 days (1–8 mg/kg). The monoclonal antibody targets HER2 on tumor cells, is internalized, and releases a cytotoxic payload to induce tumor cell death; payload not disclosed.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibody-Drug Conjugates
drug_category
ANTIBODY DRUG CONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Monoclonal antibody binds HER2 (ERBB2) on tumor cells, is internalized, and releases a linked cytotoxic payload intracellularly to kill the cancer cell; payload type not disclosed.
drug_name
SIBP-A17
nct_id_drug_ref
NCT06512116