drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
Murine anti-CD38 monoclonal antibody that targets CD38 on malignant plasma cells; used as the targeting carrier for 211At to deliver alpha radiation.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Antibodies, Monoclonal
drug_category
RADIOIMMUNOCONJUGATE
drug_class
Conjugate
drug_delivery_route
Intravenous
drug_mechanism_of_action
Murine anti-CD38 monoclonal antibody (OKT10-B10) conjugated to the alpha-emitter astatine-211; binds CD38 on malignant plasma cells and delivers short-range alpha radiation, causing dense ionization, DNA double-strand breaks, and targeted tumor cell death.
drug_name
OKT10-B10 (anti-CD38 monoclonal antibody)
nct_id_drug_ref
NCT04466475