drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
Gene-edited allogeneic universal CAR-T cell therapy using a CD94-based recognition domain to engage the CD94/HLA-E axis, designed to overcome immune evasion and enhance tumor killing.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Biological Products
drug_category
CAR T
drug_class
Cellular Therapy
drug_delivery_route
Intravenous
drug_mechanism_of_action
Gene-edited allogeneic universal CAR-T cells engineered with a CD94-based recognition domain that engages the CD94/HLA-E axis on tumor cells, overcoming immune evasion and activating T-cell cytotoxicity to kill malignant cells.
drug_name
CT7590
nct_id_drug_ref
NCT05893693