drug_type
RELEVANT_DRUG
intervention_type
Biological (autologous cell-based immunotherapy)
drug_description
Autologous dendritic cell tumor vaccine in which patient-derived dendritic cells are loaded with tumor antigens to enhance antigen presentation and activate CD8+ and CD4+ T cells to kill glioma/GBM cells.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
lentiviral minigene vaccine of COVID-19 coronavirus
drug_category
DC VACCINE
drug_class
Vaccine
drug_delivery_route
Not Reported
drug_mechanism_of_action
Autologous dendritic cells are loaded with patient tumor antigens and reinfused to enhance MHC I/II antigen presentation and co-stimulation, activating tumor-specific CD8+ cytotoxic and CD4+ helper T cells to drive immune-mediated killing of glioma/GBM cells.
drug_name
DC vaccine
nct_id_drug_ref
NCT06043232