drug_type
RELEVANT_DRUG
intervention_type
Monoclonal antibody (biologic)
drug_description
An intravenous anti-BAFF receptor (BAFF-R) monoclonal antibody that blocks BAFF signaling, depletes B cells, and reduces autoantibody production.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Ianalumab
drug_category
INHIBITORY ANTIBODY
drug_class
Inhibitor
drug_delivery_route
Intravenous
drug_mechanism_of_action
Monoclonal antibody against BAFF receptor (BAFF-R) that blocks BAFF signaling and depletes B cells (via Fc-mediated cytotoxicity), reducing autoreactive B-cell survival and autoantibody production.
drug_name
Ianalumab (VAY736)
nct_id_drug_ref
NCT05653219