drug_type
RELEVANT_DRUG
intervention_type
Biological
drug_description
Investigational adoptive cellular immunotherapy given as a single IV infusion (2.0×10^8 to 6.0×10^9 cells); BGT007H cells are intended to recognize a predefined tumor-associated antigen and mediate antigen-directed cytotoxicity against target-expressing tumor cells via cytotoxic lymphocyte mechanisms.
nci_thesaurus_definition
NCI thesaurus definition not available.
drug_mesh_term
Immunotherapy, Adoptive
drug_category
OTHER ENGINEERED IMMUNE CELL
drug_class
Cellular Therapy
drug_delivery_route
Intravenous
drug_mechanism_of_action
Adoptive transfer of genetically engineered cytotoxic lymphocytes that recognize a predefined tumor-associated antigen on tumor cells and induce antigen-directed killing via perforin/granzyme-mediated cytolysis and cytokine-driven immune activation.
drug_name
BGT007H Injection
nct_id_drug_ref
NCT06104215